Shared structural motifs in TCR of glycopeptide-recognizing T cell hybridomas
نویسندگان
چکیده
منابع مشابه
T Cell Receptor (TCR) Antagonism without a Negative Signal: Evidence from T Cell Hybridomas Expressing Two Independent TCRs
Antagonist peptides inhibit T cell responses by an unknown mechanism. By coexpressing two independent T cell receptors (TCRs) on a single T cell hybridoma, we addressed the question of whether antagonist ligands induce a dominant-negative signal that inhibits the function of a second, independent TCR. The two receptors, Valpha2Vbeta5 and Valpha2Vbeta10, restricted by H-2Kb and specific for the ...
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ژورنال
عنوان ژورنال: European Journal of Immunology
سال: 1999
ISSN: 0014-2980,1521-4141
DOI: 10.1002/(sici)1521-4141(199909)29:09<2759::aid-immu2759>3.0.co;2-4